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Interestingly, the nuclear GSH pool appears to be dynamic and independent of cytosolic GSH, undergoing major shifts in relative concentration throughout the cell cycle which reaches upwards of four times the concentration found in the cytosol [76]

Mild and temporary side effects were reported in the first four weeks and resolved by the next evaluation, indicating that the glutathione supplement might be safe to use at the described dosage for this period of time

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first reported a polymorphism in GPx1, namely, a substitution at codon 198 of either proline (Pro) or leucine (Leu), Pro198Leu (SNP: 1050450), in lung cancer [87]